abstract：:We have characterized the single subunit RNA polymerase from Klebsiella phage KP34. The enzyme is unique among known bacteriophage RNA polymerases in that it recognizes two unrelated promoter sequences, which provided clues for the evolution of phage single-subunit RNA polymerases. As the first representative enzyme f...

journal_title：Frontiers in microbiology

authors： Lu X,Wu H,Xia H,Huang F,Yan Y,Yu B,Cheng R,Drulis-Kawa Z,Zhu B

更新日期：2019-10-31 00:00:00

abstract：:The new era of multidrug resistance of pathogens against frontline antibiotics has compromised the immense therapeutic gains of the 'golden age,' stimulating a resurgence in antimicrobial research focused on antimicrobial and immunomodulatory components of botanical, fungal or microbial origin. While much valuable inf...

journal_title：Frontiers in microbiology

authors： Sadgrove NJ,Jones GL

更新日期：2019-10-31 00:00:00

abstract：:Many Gram-negative bacteria use a type VI secretion system (T6SS) for microbial warfare and/or host manipulation. Acinetobacter baumannii is an important nosocomial pathogen and many A. baumannii strains utilize a T6SS to deliver toxic effector proteins to surrounding bacterial cells. These toxic effectors are usually...

journal_title：Frontiers in microbiology

authors： Lewis JM,Deveson Lucas D,Harper M,Boyce JD

更新日期：2019-10-30 00:00:00

abstract：:CRISPR-Cas systems adapt "memories" via spacers from viruses and plasmids to develop adaptive immunity against mobile genetic elements. Mature CRISPR RNAs guide CRISPR-associated nucleases to site-specifically cleave target DNA or RNA, providing an efficient genome engineering tool for organisms of all three kingdoms....

journal_title：Frontiers in microbiology

authors： Li Y,Peng N

更新日期：2019-10-25 00:00:00

abstract：:The increased use of molecular identification methods and mass spectrometry has revealed that Acinetobacter spp. of the A. baumannii (Ab) group other than A. baumannii are increasingly being recovered from human samples and may pose a health challenge if neglected. In this study 76 isolates of 5 species within the Ab ...

journal_title：Frontiers in microbiology

authors： Cosgaya C,Ratia C,Marí-Almirall M,Rubio L,Higgins PG,Seifert H,Roca I,Vila J

更新日期：2019-10-24 00:00:00

abstract：:The recent worldwide rise in idiopathic immune and inflammatory diseases such as multiple sclerosis (MS) and inflammatory bowel diseases (IBD) has been linked to Western society-based changes in lifestyle and environment. These include decreased exposure to sunlight/UVB light and subsequent impairment in the productio...

journal_title：Frontiers in microbiology

authors： Bosman ES,Albert AY,Lui H,Dutz JP,Vallance BA

更新日期：2019-10-24 00:00:00

abstract：:Elongation factor thermal unstable Tu (EF-Tu) is a G protein that catalyzes the binding of aminoacyl-tRNA to the A-site of the ribosome inside living cells. Structural and biochemical studies have described the complex interactions needed to effect canonical function. However, EF-Tu has evolved the capacity to execute...

journal_title：Frontiers in microbiology

authors： Harvey KL,Jarocki VM,Charles IG,Djordjevic SP

更新日期：2019-10-24 00:00:00

abstract：:Streptococcus pneumoniae colonizes the upper airways of children and the elderly. Colonization progresses to persistent carriage when S. pneumoniae forms biofilms, a feature required for the development of pneumococcal disease. Nasopharyngeal biofilms are structured with a matrix that includes extracellular DNA (eDNA)...

journal_title：Frontiers in microbiology

authors： Angulo-Zamudio UA,Vidal JE,Nazmi K,Bolscher JGM,Leon-Sicairos C,Antezana BS,Canizalez-Roman A,León-Sicairos N

更新日期：2019-10-18 00:00:00

abstract：:Photobacteria are common psychrophilic bacteria found in marine environments. Recently, several studies revealed high numbers of Photobacterium (P.) spp. on packaged fresh meat. Their occurrence appears relevant for the spoilage of meat, since species of the genus are already known as potent fish spoilage organisms. H...

journal_title：Frontiers in microbiology

authors： Fuertes-Perez S,Hauschild P,Hilgarth M,Vogel RF

更新日期：2019-10-18 00:00:00

abstract：:Viruses and plasmids can introduce novel DNA into bacterial cells, thereby creating an opportunity for genome expansion; conversely, CRISPR, the prokaryotic adaptive immune system, which targets and eliminates foreign DNAs, may impair genome expansions. Recent studies presented conflicting results over the impact of C...

journal_title：Frontiers in microbiology

authors： Gao NL,Chen J,Wang T,Lercher MJ,Chen WH

更新日期：2019-10-16 00:00:00

abstract：:Cichlid fishes, with their repeated colonization of lakes and subsequent radiations at different scales of phylogenetic and ecological diversification, offer an excellent model system to understand the factors shaping the host-gut microbiota association in nature. Here, we characterized the gut microbiota of the Amphi...

journal_title：Frontiers in microbiology

authors： Baldo L,Riera JL,Salzburger W,Barluenga M

更新日期：2019-10-15 00:00:00

abstract：:Besides the major nutrients, phosphorus (P) is an essential mineral for both the host animal and the porcine gut microbiota. Different strategies including phytase supplementation and more recently lactic acid (LA) are used to enhance the P availability from cereals in pig diets; however, their impact on the gut micro...

journal_title：Frontiers in microbiology

authors： Klinsoda J,Vötterl J,Zebeli Q,Metzler-Zebeli BU

更新日期：2019-10-15 00:00:00

abstract：:Endogenous hydrogen sulfide (H2S), which is primarily generated by 3-mercaptopyruvate sulfurtransferase (3-MST) in Escherichia coli (E. coli) under aerobic conditions, renders bacteria highly resistant to oxidative stress. However, the biosynthetic pathway and physiological role of this gas under anaerobic conditions ...

journal_title：Frontiers in microbiology

authors： Wang J,Guo X,Li H,Qi H,Qian J,Yan S,Shi J,Niu W

更新日期：2019-10-11 00:00:00

abstract：:Dental caries and periodontitis are the most common oral disease of all age groups, affecting billions of people worldwide. These oral diseases are mostly associated with microbial biofilms in the oral cavity. Streptococcus gordonii, an early tooth colonizing bacterium and Candida albicans, an opportunistic pathogenic...

journal_title：Frontiers in microbiology

authors： Veerapandian R,Vediyappan G

更新日期：2019-10-11 00:00:00

abstract：:Pathogen-pathogen interactions in polymicrobial infections are known to directly impact, often to worsen, disease outcomes. For example, co-infection with Pseudomonas aeruginosa and Aspergillus fumigatus, respectively the most common bacterial and fungal pathogens isolated from cystic fibrosis (CF) airways, leads to a...

journal_title：Frontiers in microbiology

authors： Scott J,Sueiro-Olivares M,Ahmed W,Heddergott C,Zhao C,Thomas R,Bromley M,Latgé JP,Krappmann S,Fowler S,Bignell E,Amich J

更新日期：2019-10-09 00:00:00

abstract：:Ocular toxoplasmosis (OT) is one of the most common causes of posterior uveitis. The signaling of triggering receptor expressed on myeloid cells (TREM)-1 amplifies inflammation, whereas TREM-2 signaling is anti-inflammatory. IL-1β is a major driver of inflammation during infection. Toll-like receptors (TLRs) play impo...

journal_title：Frontiers in microbiology

authors： Zhang Y,He J,Zheng H,Huang S,Lu F

更新日期：2019-10-09 00:00:00

abstract：:The gastrointestinal tract is an ideal habitat for diverse bacterial species that reside in a homeostatic balance with local tissue and significantly contribute to host health. Negative shifts in gut microbiota profiles, also known as dysbiosis, may be implicated in the development of chronic disorders such as inflamm...

journal_title：Frontiers in microbiology

authors： Babbar A,Hitch TCA,Pabst O,Clavel T,Hübel J,Eswaran S,Wagner N,Schippers A

更新日期：2019-10-04 00:00:00

abstract：Rationale:Although frequently retrieved in tracheal secretions of critically ill patients on mechanical ventilation, the existence of pneumonia caused by coagulase-negative staphylococci (CoNS) remains controversial. Objective:To assess whether Staphylococcus haemolyticus (S. haemolyticus) inoculated in mice's trachea...

journal_title：Frontiers in microbiology

authors： Shi MM,Monsel A,Rouby JJ,Xu YP,Zhu YG,Qu JM

更新日期：2019-10-04 00:00:00

abstract：:Three chemical epigenetic modifiers [5-azacytidine, nicotinamide, and suberoylanilide hydroxamic acid (SAHA)] were applied to induce the metabolites of Penicillium mallochii CCH01, a fungus isolated from the gut of Ectropis oblique. Metabolite profiles of P. mallochii CCH01 were obviously changed by SAHA treatment. Fo...

journal_title：Frontiers in microbiology

authors： Zhang S,Fang H,Yin C,Wei C,Hu J,Zhang Y

更新日期：2019-10-02 00:00:00

abstract：:Capsular polysaccharides (CPS), a major virulence factor in Streptococcus pneumoniae, become thicker during blood invasion while not during asymptomatic nasopharyngeal colonization. However, the underlying mechanism controlling this differential pneumococcal CPS regulation remain unclear. Here, we show how VncR, the r...

journal_title：Frontiers in microbiology

authors： Ghosh P,Shah M,Ravichandran S,Park SS,Iqbal H,Choi S,Kim KK,Rhee DK

更新日期：2019-10-01 00:00:00

abstract：:The taxonomically diverse rhizosphere microbiome contributes to plant nutrition, growth and health, including protection against soil-borne pathogens. We previously showed that breeding for Fusarium-resistance in common bean changed the rhizosphere microbiome composition and functioning. Here, we assessed the impact o...

journal_title：Frontiers in microbiology

authors： Mendes LW,de Chaves MG,Fonseca MC,Mendes R,Raaijmakers JM,Tsai SM

更新日期：2019-10-01 00:00:00

abstract：:Deep fractured rock ecosystems across most of North America have not been studied extensively. However, the US Great Basin, in particular the Nevada National Security Site (NNSS, formerly the Nevada Test Site), has hosted a number of influential subsurface investigations over the years. This investigation focuses on r...

journal_title：Frontiers in microbiology

authors： Hamilton-Brehm SD,Stewart LE,Zavarin M,Caldwell M,Lawson PA,Onstott TC,Grzymski J,Neveux I,Lollar BS,Russell CE,Moser DP

更新日期：2019-09-27 00:00:00

abstract：:Bark beetles from Dendroctonus genus promote ecological succession and nutrient cycling in coniferous forests. However, they can trigger outbreaks leading to important economic losses in the forest industry. Conifers have evolved resistance mechanisms that can be toxic to insects but at the same time, bark beetles are...

journal_title：Frontiers in microbiology

authors： Soto-Robles LV,Torres-Banda V,Rivera-Orduña FN,Curiel-Quesada E,Hidalgo-Lara ME,Zúñiga G

更新日期：2019-09-27 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fmicb.2018.02507.]. ...

journal_title：Frontiers in microbiology

authors： Khan N,Zandi P,Ali S,Mehmood A,Adnan Shahid M,Yang J

更新日期：2019-09-27 00:00:00

abstract：:Bacterial conjugation is one of the most important mechanisms for spread of antibiotic resistance among bacteria. We have previously demonstrated that cefotaxime (CTX) exposure up-regulates expression of Type-IV conjugation transfer genes, and that this leads to increased transfer of a blaCTX-M-1 encoding IncI1 resist...

journal_title：Frontiers in microbiology

authors： Liu G,Olsen JE,Thomsen LE

更新日期：2019-09-24 00:00:00

abstract：:The amendment of crop residues produced under elevated CO2 (eCO2) may alter soil microbial community structure and their functions on residue decomposition and carbon (C) cycling in soil. The key to understanding this process is to elucidate the structure of prokaryotic communities that metabolize crop residues derive...

journal_title：Frontiers in microbiology

authors： Wang Y,Yu Z,Li Y,Wang G,Tang C,Liu X,Liu J,Xie Z,Jin J

更新日期：2019-09-24 00:00:00

abstract：:The physiological heterogeneity of cells within a microbial population imparts resilience to stresses such as antimicrobial treatments and nutrient limitation. This resilience is partially due to a subpopulation of cells that can survive such stresses and regenerate the community. Microfluidic approaches now provide a...

journal_title：Frontiers in microbiology

authors： Pratt SL,Zath GK,Akiyama T,Williamson KS,Franklin MJ,Chang CB

更新日期：2019-09-24 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fmicb.2019.01752.]. ...

journal_title：Frontiers in microbiology

authors： Frontiers Production Office.

更新日期：2019-09-24 00:00:00

abstract：:Rice is a major staple food across the globe. Its growth and productivity is highly dependent on the rhizobiome where crosstalk takes place between plant and the microbial community. Such interactions lead to selective enrichment of plant beneficial microbes which ultimately defines the crop health and productivity. I...

journal_title：Frontiers in microbiology

authors： Imchen M,Kumavath R,Vaz ABM,Góes-Neto A,Barh D,Ghosh P,Kozyrovska N,Podolich O,Azevedo V

更新日期：2019-09-20 00:00:00

abstract：:Pseudomonas aeruginosa (PA) is the leading cause of corneal blindness worldwide. A constant increase in multi-drug resistant PA strains have heightened the challenge of effectively managing corneal infections with conventional antibiotics. Antimicrobial peptides are promising antibiotic analogs with a unique mode of a...

journal_title：Frontiers in microbiology

authors： Mohammed I,Said DG,Nubile M,Mastropasqua L,Dua HS

更新日期：2019-09-19 00:00:00

abstract：:Colonizing germ-free (GF) zebrafish with specific bacterial species provides the possibility of understanding the influence on host biological processes including gene expression, development, immunity, and behavioral responses. It also enlightens our understanding on the host-microbe interactions within the physiolog...

journal_title：Frontiers in microbiology

authors： Tan F,Limbu SM,Qian Y,Qiao F,Du ZY,Zhang M

更新日期：2019-09-18 00:00:00

abstract：:Gut microbes play a crucial role in the development of colorectal cancer. Chitooligosaccharides (COS), are oligomer that are depolymerized from chitosan and possess a wide range of biological activities. In this study, the effects of COS on colorectal cancer (CRC) development were evaluated using azoxymethane and dext...

journal_title：Frontiers in microbiology

authors： Wu M,Li J,An Y,Li P,Xiong W,Li J,Yan D,Wang M,Zhong G

更新日期：2019-09-18 00:00:00

abstract：:Type VI CRISPR-Cas systems contain a single effector nuclease (Cas13) that exclusively targets single-stranded RNA. It remains unknown how these systems acquire spacers. It has been suggested that type VI systems with adaptation modules can acquire spacers from RNA bacteriophages, but sequence similarities suggest tha...

journal_title：Frontiers in microbiology

authors： Toro N,Mestre MR,Martínez-Abarca F,González-Delgado A

更新日期：2019-09-13 00:00:00

abstract：:Tuberculosis is still a major threat to global public health. Here, a novel diagnosis assay, termed as multiple cross displacement amplification combined with nanoparticle-based lateral flow biosensor (MCDA-LFB), was developed to simultaneously detect IS6110 and IS1081 of Mycobacterium tuberculosis (MTB) in DNA extrac...

journal_title：Frontiers in microbiology

authors： Jiao WW,Wang Y,Wang GR,Wang YC,Xiao J,Sun L,Li JQ,Wen SA,Zhang TT,Ma Q,Huang HR,Shen AD

更新日期：2019-09-13 00:00:00

abstract：:Extended-spectrum beta-lactamase- (ESBL-) and AmpC beta-lactamase- (AmpC-) producing Enterobacteriaceae pose a risk for both human and animal health. For livestock, highest prevalences have been reported in broiler chickens, which are therefore considered as a reservoir of multidrug-resistant bacteria. The possibility...

journal_title：Frontiers in microbiology

authors： Robé C,Blasse A,Merle R,Friese A,Roesler U,Guenther S

更新日期：2019-09-13 00:00:00

abstract：:The microbiome within a poultry production house influences the attainment of physiologically strong birds and thus food safety and public health. Yet little is known about the microbial communities within the house and the effects on the soil microbes onto which the houses are placed; nor the effects of management pr...

journal_title：Frontiers in microbiology

authors： Crippen TL,Sheffield CL,Singh B,Byrd JA,Beier RC

更新日期：2019-09-13 00:00:00

abstract：:Listeria monocytogenes (Lm) is a common environmental bacterium that thrives on vegetation and soil matter, but can infect humans if contaminated food products are ingested, resulting in severe disease in immunosuppressed populations, including pregnant women and newborns. To better understand how the unique immunolog...

journal_title：Frontiers in microbiology

authors： Wolfe B,Kerr AR,Mejia A,Simmons HA,Czuprynski CJ,Golos TG

更新日期：2019-09-11 00:00:00

abstract：:In this study, mixed starter cultures of yeast and lactobacilli were used for type I sourdough bread making to evaluate their ability to improve bread quality and increase the amount of flavor volatiles. Kazachstania humilis, Saccharomyces cerevisiae, Wickerhamomyces anomalus, and Lactobacillus sanfranciscensis DSM204...

journal_title：Frontiers in microbiology

authors： Xu D,Zhang Y,Tang K,Hu Y,Xu X,Gänzle MG

更新日期：2019-09-10 00:00:00

abstract：:In bacteria, the GntR family is a widespread family of transcription factors responsible for the regulation of a myriad of biological processes. In contrast, despite their occurrence in archaea only a little information is available on the function of GntR-like transcription factors in this domain of life. The thermoa...

journal_title：Frontiers in microbiology

authors： Lemmens L,Tilleman L,De Koning E,Valegård K,Lindås AC,Van Nieuwerburgh F,Maes D,Peeters E

更新日期：2019-09-10 00:00:00

abstract：:The Gram-negative bacterium Vibrio cholerae encodes two nucleases, Dns and Xds, which play a major role during the human pathogen's lifecycle. Dns and Xds control three-dimensional biofilm formation and bacterial detachment from biofilms via degradation of extracellular DNA and thus contribute to the environmental, in...

journal_title：Frontiers in microbiology

authors： Pressler K,Mitterer F,Vorkapic D,Reidl J,Oberer M,Schild S

更新日期：2019-09-10 00:00:00